Arthritis

"If I was an arthritic individual, I would be eliminating every possible source of fluoride exposure that I could think of." (Phyllis Mullenix, PhD, Toxicologist)

Gastrointestinal

"Studies are needed to evaluate gastric responses to fluoride from natural sources at concentrations up to 4 mg/L and from artificial sources." - (National Research Council, 2006)

Bone Fracture

"One cannot help but be alarmed by the negative effects of fluoride on bone strength consistently demonstrated in animal models." - Dr. Charles Turner, Indiana University.

Hypersensitivity

"In hypersensitive individuals, fluorides occasionally cause skin eruptions such as atopic dermatitis, eczema or urticaria. Gastric distress, headache and weakness have also been reported. These hypersensitivity reactions usually disappear promptly after discontinuation of the fluoride." - PHYSICIAN'S DESK REFERENCE

Brain Effects

"It is apparent that fluorides have the ability to interfere with the functions of the brain." (National Research Council, 2006)

Kidney Disease

"A fairly substantial body of research indicates that patients with chronic renal insufficiency are at an increased risk of chronic fluoride toxicity. These patients may develop skeletal fluorosis even at 1 ppm fluoride in the drinking water." (Dr. Helmut Schiffl, 2008)

Cancer
"We observed that for males diagnosed before the age of 20 years, fluoride level in drinking water during growth was associated with an increased risk of osteosarcoma, demonstrating a peak in the odds ratios from 6 to 8 years of age. All of our models were remarkably robust in showing this effect, which coincides with the mid-childhood growth spurt." (Bassin, et al., Cancer, Causes & Control, 2006)

Male Fertility
"The enhancing overload caused by fluorides represents a potential factor, having an impact on function of sperm, hence contributing to a growing infertility in the human population." (Animal Reproduction Science, 2008)

Cardiovascular Disease
"Our study shows that the severity of skeletal fluorosis is directly related to the severity of abnormal cardiac function, as demonstrated by the electrocardiograms. The results show that fluoride in drinking water consumed over time is harmful not only to bones and teeth but also to the cardiovascular system..." (Fluoride, 1997)

Pineal Gland
"Fluoride is likely to cause decreased melatonin production and to have other effects on normal pineal function, which in turn could contribute to a variety of effects in humans." (National Research Council 2006).

Diabetes
"The conclusion from the available studies is that sufficient fluoride exposure appears to bring about increases in blood glucose or impaired glucose tolerance in some individuals and to increase the severity of some types of diabetes." (National Research Council, 2006)

Skeletal Fluorosis
"Although skeletal fluorosis has been studied intensely in other countries for more than 40 years, virtually no research has been done in the U.S. to determine how many people are afflicted with the earlier stages of the disease, particularly the preclinical stages." - Chemical & Engineering News

Endocrine Disruption
"In summary, evidence of several types indicates that fluoride affects normal endocrine function or response; the effects of the fluoride-induced changes vary in degree and kind in different individuals. Fluoride is therefore an endocrine disruptor in the broad sense of altering normal endocrine function or response." (National Research Council, 2006)

Thyroid Disease
"The effects of fluoride on various aspects of endocrine function should be examined, particularly with respect to a possible role in the development of several diseases or mental states in the United States. Major areas of investigation include . . . thyroid disease (especially in light of decreasing iodine intake by the U.S. population)." (National Research Council 2006).

Acute Toxicity
"Parents or caregivers may not notice the symptoms associated with mild fluoride toxicity or may attribute them to colic or gastroenteritis, particularly if they did not see the child ingest fluoride." (Journal of Public Health Dentistry, 1997)